hands wearing medical gloves injecting syringe on client s face

Tox Frequency: What Patients Should Know

This is a topic of conversation that you hear quite often in small groups of injectors discussing comments from some of their patients on whether or not the tox “is working any more.” According to a recent article on MSN.com, immunity is incredibly rare, but resistance is something that can happen. NY-based plastic surgeon, Brian Bassiri-Tehrani, MD, told The Daily Mail that this resistance can happen when patients are exposed more frequently, as well as being exposed to higher doses.

“People who will dose or touch up Botox in between the regular three-month sessions might be at risk,” Dr. Bassiri-Tehrani said. “Another thing that people don’t fully realize about [tox] is that once it goes into the neuromuscular junction it binds to the nerve endings that are powering the muscle, and it doesn’t just come off in three months, and everything’s fine. It permanently attaches to those nerve endings, and what happens is new nerve endings go into the muscles.
So the reason it wears off in three months isn’t because the [tox] disappears. It’s because new nerve endings are now innervating those muscle units, and when they reinnervate the muscle units, they’re not reinnervating the exact same muscle units exactly the same way,” he continued. Bassiri-Tehrani suggests waiting every six months for new nerve endings to take root and heal.

Recently, celebrity dermatologist Dr. Paul Frank was interviewed by the New York Post and compared receiving tox to regular beauty grooming as opposed to cosmetic medicine, which can result in patients wanting it more frequently and in larger amounts. This is something that very likely will result in tox becoming less efficient for those particular patients over time, and something that practitioners should be warning against to frequent patients.

https://www.msn.com/en-us/health/other/botox-use-has-become-so-frequent-that-youth-chasers-are-developing-immunity-to-the-injectable-doctors/

https://www.dailymail.co.uk/femail/article-14495679/expert-women-immune-botox-prevent.html

https://nypost.com/2024/04/23/lifestyle/new-yorkers-weigh-in-on-once-taboo-botox-and-how-often-they-get-it

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